Treatments with goji extracts increased serum testosterone level, increased the expression of endothelial NO synthase, neuronal NO synthase, and cGMP, improved the oxidative stress marker, and decreased corporal fibrosis. After 6 weeks of treatment, testes weight, serum testosterone, superoxide dismutase, nitric oxide (NO)-cyclic guanosine monophosphate (cGMP)-related parameters, intracavernous pressure/mean arterial pressure, and histological changes were examined. Treatment was by orogastric tube once daily for 6 weeks. Treatment groups contained eight rats each: a control group, goji extract of 150 mg/kg/day group, and goji extract of 300 mg/kg/day group. Twenty-four 18-month-old male Sprague-Dawley rats (defined as old-aged rats) were used.
This study investigated the effect of goji (Lycium chinense Mill.) on erectile dysfunction in old-aged rats. Given the lack of FDA oversight of many other supplements similar to this one, patients must be wary that the ingredients listed may not be comprehensive and that serious side effects can occur. Interestingly, since our initial contact with the FDA Safety Reporting Portal, multiple investigations of Rhino products have demonstrated that sildenafil is a non-labeled ingredient.
We are unaware of any studies regarding Rhino 7 Platinum 3000. There are few studies performed and few case reports regarding the roles of various supplements in causing priapism. On initial 2-week follow-up, he had significant fibrosis of the corporal bodies bilaterally and had been unable to achieve an erection. He required bilateral corpo-glanular shunting to alleviate his priapism. A 25-year-old man presented with a 48-h priapism after taking Rhino 7 Platinum 3000. Longstanding priapism is a significant potential side effect. Male enhancement and erectile dysfunction supplements are typically non-Food and Drug Administration (FDA) approved and readily available for purchase by anyone.
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